Personel

Doç.Dr. REŞAT ÜNAL
Doç.Dr.
Reşat Ünal
@ E-posta
resatunal@mu.edu.tr
Telefon
0252 211 5586 , 0252 211 5633

Kadro Bilgileri

Görev Birimi

Uluslararası İlişkiler Koordinatörlüğü

Kadro Birimi

Fen Fakültesi / Moleküler Biyoloji Ve Genetik Bölümü / Moleküler Hücre Biyolojisi Abd

Öğrenim Bilgileri

Lisans

Hacettepe Üniversitesi Fen Fakültesi, Biyoloji Bölümü, Ankara/Türkiye 1996

Yüksek Lisans

Bilkent Üniversitesi Fen Bilimleri Enstitüsü, Moleküler Biyoloji ve Genetik Anabilim Dalı, Ankara/Türkiye 1998

Doktora

Karlsruhe Institute of Technology (KIT), Institute of Toxicology and Genetics (ITG), Karlsruhe/Germany 2003

Yayin Bilgileri

(A-1) SCI veya SCI Expanded, SSCI, AHCI tarafından taranan dergilerde yayımlanan tam makale

1-) Kirby, T.J., Walton, G., Finlin, B., Zhu, B., Unal, R., Rasouli, N., Peterson, C., Kern, P., 2016. Integrative mRNA-microRNA analyses reveal novel interactions related to insulin sensitivity in human adipose tissue.. Physiological Genomics
2-) Walton, R., Zhu, B., Unal, R., Spencer, M., Sunkara, M., Morris, A., Charnigo, R., Katz, W., Daugherty, A., Howatt, D., 2015. Increasing Adipocyte Lipoprotein Lipase Improves Glucose Metabolism in High Fat Diet Induced Obesity. Journal of Biological Chemistry
3-) Spencer, M., Finlin, B., Unal, R., Zhu, B., Morris, A., Shipp, L., Lee, J., Walton, R., Adu, A., Erfani, R., 2013. Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects with Insulin Resistance. Diabetes
4-) Ranganathan, G., Unal, R., Pokrovskaya, I.D., Tripathi, P., Rotter, J.I., Goodarzi, M.O., Kern, P.A., 2012. The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation. Atherosclerosis
5-) Spencer, M., Unal, R., Zhu, B., Rasouli, N., Mcgehee, R.J., Peterson, C., Kern, P., 2011. Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance. Journal of Clinical Endocrinology and Metabolism
6-) Spencer, M., Yao, A., Unal, R., Rasouli, N., Gurley, C., Zhu, B., Peterson, C., Kern, P., 2010. Adipose tissue macrophages in insulin resistant subjects are associated with collagen VI, fibrosis and demonstrate alternative activation. American Journal of Physiology, Endocrinology and Metabolism
7-) Unal, R., Yao, A., Varma, V., Rasouli, N., Labbate, C., Kern, P., Ranganathan, G., 2010. Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone. Journal of Clinical Endocrinology and Metabolism
8-) Banga, A., Unal, R., Tripathi, P., Pokrovskaya, I., Owens, R., Kern, P., Ranganathan, G., 2009. Adiponectin translation is increased by the PPAR gamma agonists pioglitazone and w-3 fatty acids. American Journal of Physiology, Endocrinology and Metabolism
9-) Yao, A., Rassouli, N., Varma, V., Bodles, A., Rasouli, N., Unal, R., Phanavanh, B., Ranganathan, G., Mcgehee, R.J., Kern, P., 2008. Stearoyl-CoA Desaturase 1 (SCD1) Gene Expression increases following piogitazone treatment and is associated with PPAR gamma responsiveness in Humans. Journal of Clinical Endocrinology and Metabolism
10-) Unal, R., Pokrovskaya, I., Tripathi, P., Monia, B., Kern, P., Ranganathan, G., 2008. Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase C alpha activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA. Biochemical Journal
11-) Ahmed, B., Jeffus, B., Bukhari, S., Harney, J., Unal, R., Lupashin, V., Van Der Slujs, P., Kilic, F., 2008. Serotonin Transamidates Rab4 and Facilitates Its Binding to the C-Terminus of SERT. Journal of Biological Chemistry
12-) Brenner, B., Harney, J., Ahmed, B., Jeffus, B., Unal, R., Mehta, J., Kilic, F., 2007. Plasma Serotonin Levels and the Platelet Serotonin Transporter. Journal of Neurochemistry
13-) Unal, R., Ahmed, B., Jeffus, B., Harney, J., Lyle, C., K., Y., Chambers, T., Reece, E., Kilic, F., 2007. At diabetes-like concentration glucose down-regulates the placental serotonin transport system. Journal of Neurochemistry
14-) Ranganathan, G., Unal, R., Pokrovskaya, I., Yao, A., Phanavanh, B., Lecka, B., Rasouli, N., Kern, P., 2006. The lipogenic enzymes DGAT1, FAS and LPL in adipose tissue: effects of obesity, insulin resistance and TZD treatment.” , 2006 Nov; 47(11):2444-2450. Journal of Lipid Research

(A-5) SCI veya SCI Expanded, SSCI, AHCI dışındaki uluslararası indexler tarafından taranan dergilerde yayımlanan tam makale

1-) Altan, F., Ünal, R., 2014. Focus on Proteomics and Bioinformatics in Translational Research and Plant Research of Obesity and Diabetes. MOJ Proteomics and Bioinformatics

(B-1) Uluslararası kongre, sempozyum, panel, çalıştay gibi bilimsel, sanatsal toplantılarda sözlü olarak sunulan ve tam metin olarak yayımlanan bildiri

1-) Muniappan, L., Unal, R., Finlin, B., Peterson, C., Kern, P., 2012. Expression of miR 17-92 cluster in adipose tissue: potential role in the regulation of fibrosis and angiogenesis. American Diabetes Association 72th Annual Scientific Sessions
2-) Spencer M., Nasser M., Unal R., Zhu B., Rasouli N., Peterson CA. and Kern PA . “Adipose Tissue Extracellular Matrix and Vascular Abnormalities in Obesity and Insulin Resistance.” , 2011 Jun 24-28; American Diabetes Association 71th Annual Scientific Sessions, San Diego, CA - 2011
3-) Michael Spencer, Munira Nasser, Resat Unal, Beibei Zhu, Neda Rasouli, Charlotte A Peterson, Philip A Kern, 2011. Adipose Tissue Extracellular Matrix and Vascular Abnormalities in Obesity and Insulin Resistance. American Diabetes Association 71th Annual Scientific Sessions

(B-3) Uluslararası kongre, sempozyum, panel, çalıştay gibi bilimsel, sanatsal toplantılarda poster şeklinde sunulan ve özet metin olarak yayımlanan bildiri.

1-) Spencer, M., Finlin, B., Unal, R., Zhu, B., Morris, A., Shipp, L., Lee, J., Walton, R., Adu, A., Erfani, R., Campbell, M., Mcgehee, R.J., Peterson, C., Kern, P., 2013. The Effect of Omega-3 Fatty Acids on Adipose Tissue Macrophages in Human Subjects with Insulin Resistance. MolBiyoKon Second International Congress of the Molecular Biology Association of Turkey
2-) Michael Spencer, Aiwei Yao Borengasser, Resat Unal, Neda Rasouli, Catherine Gurley, Charlotte A Peterson, Philip A Kern, 2010. Adipose Tissue AT Macrophages Macs in Insulin Resistant Subjects are Associated with Collagen VI Fibrosis and Demonstrate Alternative Activation. American Diabetes Association 70th Annual Scientific Sessions
3-) Spencer M., Yao-Borengasser A., Unal R., Rasouli N., Gurley C., Peterson CA and Kern PA. “Adipose Tissue (AT) Macrophages (Macs) in Insulin Resistant Subjects are Associated with Collagen VI, Fibrosis and Demonstrate Alternative Activation.” , 2010 Jun 25-29; American Diabetes Association 70th Annual Scientific Sessions, Orlando, FL - 2010
4-) Unal R., Yao-Borengasser A., Varma V., Rasouli N., Phanavanh P., Labbate C., Monia BP, Kern PA and Ranganathan G. “Matrix Metalloproteinase-9: association with insulin resistance and obesity and PKC alpha mediated regulation by pioglitazone.” , 2009 Jun 5-9; American Diabetes Association 69th Annual Scientific Sessions, New Orleans, LA - 2009
5-) Ranganathan G., Pokrovskaya ID., Unal R., Tripathi P. and Kern PA. “Lipoprotein Lipase (LPL) gain of function polymorphism involves a change in LPL translation in response to inhibitors. " , 2009 Jun 5-9; American Diabetes Association 69th Annual Scientific Sessions, New Orleans, LA - 2009
6-) Gouri Ranganathan, Irina D Pokrovskaya, Resat Unal, Preeti Tripathi, Philip A Kern, 2009. Lipoprotein Lipase LPL gain of function polymorphism involves a change in LPL translation in response to inhibitors. American Diabetes Association 69th Annual Scientific Sessions
7-) Resat Unal, Aiwei Yao Borengasser, Vijayalaksmi Varma, Neda Rasouli, Bounleut Phanavanh, Craig Labbate, Brett P Monia, Philip A Kern, Gouri Ranganathan, 2009. Matrix Metalloproteinase 9 association with insulin resistance and obesity and PKC alpha mediated regulation by pioglitazone. American Diabetes Association 69th Annual Scientific Sessions
8-) Annanya Banga, Resat Unal, Randall J Owens, Philip A Kern, Gouri Ranganathan, 2008. Up Regulation of Adiponectin Translation by Pioglitazone or omega 3 Fatty acids. American Diabetes Association 68th Annual Scientific Sessions
9-) Banga A., Unal R., Owens RJ., Kern PA. and Ranganathan G. “Up-Regulation of Adiponectin Translation by Pioglitazone or w-3 Fatty acids.” , 2008 Jun 6-10; American Diabetes Association 68th Annual Scientific Sessions, San Francisco, CA - 2008
10-) Yao, A., Rassouli, N., Varma, V., Bodles, A., Rasouli, N., Unal, R., Phanavanh, B., Mcgehee, R.J., Kern, P., 2008. Stearoyl-CoA Desaturase 1 (SCD1) Gene Expression Increases Following Pioglitazone Treatment and is Associated with PPAR gamma Responsiveness in Humans. American Diabetes Association 68th Annual Scientific Sessions
11-) Ranganathan G., Unal R., Tripathi P. and Kern PA. “Regulation of Adipose Tissue Lipoprotein Lipase by Thyroid Hormone.” , 2007 Jun 22-26; American Diabetes Association 67th Annual Scientific Sessions, Chicago, IL - 2007
12-) Unal R., Pokrovskaya I., Tripathi P., Monia BP., Kern PA. and Ranganathan G. " Inhibition of LPL by PKC alpha depletion in adipocytes involves PKA activation" , 2007 Apr 28-May 2; Experimental Biology Annual Meeting, Washington DC - 2007
13-) Gouri Ranganathan, Resat Unal, Preeti Tripathi, Philip A Kern, 2007. Regulation of Adipose Tissue Lipoprotein Lipase by Thyroid Hormone. American Diabetes Association 67th Annual Scientific Sessions
14-) Resat Unal, Irina Pokrovskaya, Preeti Tripathi, Philip A Kern, Gouri Ranganathan, 2007. Inhibition of LPL by PKC alpha depletion in adipocytes involves PKA activation. 2007 Experimental Biology Annual Meeting

(C-2) Alanında tanınmış ulusal yayınevlerince yayımlanan kitap yazarlığı

1-) Ünal Reşat, 2019. Becker’in Hücre Dünyası/Hücre Biyolojisine Bir Bakış. Yayın Evi: PALME YAYINEVİ Editör Adı: ALİ OSMAN BELDÜZ

(C-3) Alanında tanınmış uluslararası yayınevlerince yayımlanan kitaplarda bölüm yazarlığı

1-) Resat Unal, Falk Weih, Hubert Schorle, Resat Unal, 2004. BiomaterialsFrom Molecules to Engineered TissuesAdvances in Experimental Medicine and Biology/Towards dissecting the complexity of the AP-1 (activator protein 1) family.. Yayın Evi: Kluwer Academic/Plenum Publishers Editör Adı: Nesrin Hasirci, Vasif Hasirci
2-) Unal R., Weih F., Schorle H. and Herrlich P. “Towards dissecting the complexity of the AP-1 (activator protein 1) family.” , 2004; Biomaterials: From Molecules to Engineered Tissues, Vol. 553, 331-336. Kluwer Academic/Plenum Publishing Corporation, New York, ISBN: 0-306-48583-4 - 2004

(D-10) SCI veya SCI-Expanded, SSCI ve AHCI tarafından taranan dergilerde hakemlik

1-) Archieves of Physiology and Biochemistry - 2014
2-) Biomaterials - 2012
3-) Turk Biyokimya Dergisi/Turkish Journal of Biochemistry - 2012

(D-11) SCI veya SCI-Expanded, SSCI ve AHCI dışındaki uluslararası indexlerde taranan dergilerde hakemlik

1-) Meta Gene - 2014
2-) Turgut Özal Tıp Merkezi Dergisi/Journal of Turgut Ozal Medical Center - 2014

(D-6) SCI veya SCI-Expanded, SSCI ve AHCI dışındaki uluslararası indekslerde taranan dergilerde yardımcı editörlük/ alan editörlüğü ya da yayın kurulu üyeliği

1-) Editörlük Türü: Dergi. 2017. Meta Gene.
2-) Editörlük Türü: Dergi. 2014. MOJ Proteomics and Bioinformatics.

(E-1) SCI veya SCI-Expanded, SSCI ve AHCI tarafından taranan dergilerde olmak üzere adayın yazar olarak yer almadığı SCI veya SCI-Expanded, SSCI ve AHCI tarafından taranan yayınlarda adayın eserlerine yapılan atıf.

1-) Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance - Atıf Yılı: 2020 Atıf Sayısı: 8
2-) Adipose tissue macrophages in insulin resistant subjects are associated with collagen VI, fibrosis and demonstrate alternative activation - Atıf Yılı: 2020 Atıf Sayısı: 7
3-) Adiponectin translation is increased by the PPAR gamma agonists pioglitazone and w-3 fatty acids - Atıf Yılı: 2020 Atıf Sayısı: 10
4-) Plasma Serotonin Levels and the Platelet Serotonin Transporter - Atıf Yılı: 2020 Atıf Sayısı: 4
5-) At diabetes-like concentration glucose down-regulates the placental serotonin transport system - Atıf Yılı: 2020 Atıf Sayısı: 1
6-) The lipogenic enzymes DGAT1, FAS and LPL in adipose tissue: effects of obesity, insulin resistance and TZD treatment.” , 2006 Nov; 47(11):2444-2450 - Atıf Yılı: 2020 Atıf Sayısı: 5
7-) Increasing Adipocyte Lipoprotein Lipase Improves Glucose Metabolism in High Fat Diet Induced Obesity - Atıf Yılı: 2020 Atıf Sayısı: 3
8-) Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects with Insulin Resistance - Atıf Yılı: 2020 Atıf Sayısı: 8
9-) Integrative mRNA-microRNA analyses reveal novel interactions related to insulin sensitivity in human adipose tissue. - Atıf Yılı: 2020 Atıf Sayısı: 2

(F-1) Yönetiminde tamamlanmış doktora/tıpta uzmanlık/sanatta yeterlilik tezleri.

1-) Tez Adı: Catharanthus roseus L. BİTKİ ÖZÜTLERİNİN 3T3-L1 FARE HÜCRE HATLARINDA BAZI OBEZİTE VE İNSÜLİN DİRENCİ MARKÖRLERİNE OLAN ETKİSİ. Konu: Fare 3T3-L1 hücrelerinde obezite ve diyabete ilişkin birtakım belirteçler kullanılarak transkripsiyonel düzeyde regülasyon analizi.. GÜLBEN-UYTAN. 2020

(G-2) Uluslar arası kuruluşlarca desteklenen ve tamamlanan projede görev(araştırmacı, eğitmen, danışman, vb. olarak)

1-) Balık Yağının Enflamasyon ve Metabolik Sendrom Üzerindeki Etkileri (“Effects of Fish Oil on Inflammation and Metabolic Syndrome”) - 2009
2-) Obezitede Metabolik Sendromun Altında Yatan Mekanizmalar ("Mechanisms Underlying Metabolic Syndrome in Obesity") - 2009
3-) Adipositlerde Lipoprotein Lipaz Regülasyonu (“Regulation of Lipoprotein Lipase in Adipocytes”) - 2004

Verdiği Dersler

BINF5526 2019-2020 Bahar

ADVANCED MOLECULAR AND CELLULAR BIOLOGY

MBG 5514 2019-2020 Bahar

ÖKARYOTİK GEN EKSPRESYONU

MBG 5515 2019-2020 Bahar

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Uzmanlık Alan Dersi

MBG 5703 2019-2020 Bahar

Uzmanlık Alan Dersi

MBG 5704 2019-2020 Bahar

Uzmanlık Alan Dersi

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Rekombinant DNA Teknolojisi

MBG4004 2019-2020 Bahar

Bitirme Çalışması II

MBG4514 2019-2020 Bahar

Kök Hücre Biyolojisi

BINF5518 2019-2020 Güz

ADVANCED MOLECULAR AND CELLULAR BIOLOGY

MBG 5518 2019-2020 Güz

KANSER GENETİĞİ VE BİYOKİMYASI

MBG2001 2019-2020 Güz

Hücre Biyolojisi

MBG2011 2019-2020 Güz

Hücre Biyolojisi Laboratuvarı

MBG4003 2019-2020 Güz

Hücre Sinyal İletim Yolları

MBG4005 2019-2020 Güz

Bitirme Çalışması I

MBG4511 2019-2020 Güz

Mesleki İngilizce I

MBG 5514 2018-2019 Bahar

ÖKARYOTİK GEN EKSPRESYONU

MBG2508 2018-2019 Bahar

Lipid ve Lipoprotein Metabolizması

MBG3006 2018-2019 Bahar

Rekombinant DNA Teknolojisi

MBG4004 2018-2019 Bahar

Bitirme Çalışması II

MBG4514 2018-2019 Bahar

Kök Hücre Biyolojisi

VET1002 2018-2019 Bahar

GENETİK

BINF5518 2018-2019 Güz

ADVANCED MOLECULAR AND CELLULAR BIOLOGY

MBG 5515 2018-2019 Güz

MOLEKÜLER HÜCRE BİYOLOJİSİ

MBG2001 2018-2019 Güz

Hücre Biyolojisi

MBG2003 2018-2019 Güz

Hücre Biyolojisi Laboratuvarı

MBG3503 2018-2019 Güz

Protein Saflaştırma Teknikleri

MBG3511 2018-2019 Güz

Temel Moleküler Endokrinoloji

MBG4003 2018-2019 Güz

Hücre Sinyal İletim Yolları

MBG4005 2018-2019 Güz

Bitirme Çalışması I

VET1001 2018-2019 Güz

MEDİKAL BİYOLOJİ